Global Health Library (TropIKA)

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Este artigo Wiki organiza e apresenta as estratégias de busca do Portal TropIKA, utilizado para gerar o processamento e atualização para novos documentos inclusos neste Portal.

The search strategies for each type of research were developed based on the following “knowledge” defined by GFHR:

Keywords for BASIC RESEARCH: Cellular *, molecular *, genetics, genom*, disease transmission, pathogen*, vector, in vitro, immune response, enzyme*, physiology, pathology, immunology, fundamental*, biologic*, nonhuman subjects, pathogenesis, markers of infection, drug resistance, insecticide resistance

Keywords for IMPLEMENTATION RESEARCH: Implementation research, operational research, operations research, evaluation, monitoring, community-based research, participatory research, Phase IV, post-registration, efficiency, effectiveness, intervention, technology transfer, health systems research, health systems strenghtening, public health intervention, prevention strategies, control strategies, health services, * access research, field trial, acceptability, imputability, compliance , community-based (health) intervention, community-directed intervention, translational research, knowledge translation, knowledge management, Good practices

Keywords for PRODUCT DEVELOPMENT: Phase I, Phase II, Phase III, clinical trial, pre-clinical trial, double-blind trial, sequential trial, stratified trial, diagnostic testing, diagnostic development, drug testing, drug development, product testing, product development, vaccine testing, vaccine development, clinical testing, clinical development, randomized*, cross over, pharmaco*, minimal dose, maximal dose, lethal dose, toxic dose, therapeutic dose, placebo effect

Estratégias de busca

Basic Research

(((tw cellular or tw molecular or tw genetics or tw genom$ or (tw disease and tw transmission) or tw pathogen$ or ti vitro or ((tw immune$ or tw immunogen$ or tw immunol$ or tw immunop$ or tw immunod$) and (tw response or (tw effect or ti effect or tw effects or ti effects) or tw parameter$)) or tw enzym$ or tw physiology or tw pathology or ti immunology or ti fundamental$ or ti biologic$ or (tw markers and tw infection) or ti dna or (tw protein and tw physiological) or ((tw drug or tw insecticide or tw antibiotic$ or tw parasite) and tw resistance) or tw biomarkers or ((tw cell or tw parasite) and (tw characterization or tw line or tw epithelial or tw proliferation or tw survival or tw physiological)) or tw immunomodulator$ or tw immunodominant$ or (tw immunity and (tw virus or tw infection)) or tw gametocytes or (tw crystal and tw structure) or tw immunoblotting or ti mice or ti rats or tw chemokine$ or tw immunopathogenesis or ti immunodeficiency or ti immunocompetent or ti inhibitors or (tw polyclonal and tw activation) or (tw hav and tw virus) or tw macrophage$ or (tw pathogenic and tw action) or tw autoantibodies or tw autoantibody or (tw bacterial and tw proteins) or (tw antigenic and tw proteins) or ti vector or ti vectors or ((tw gene or tw genes) and (tw variant$ or tw variable$)) or ((tw antibody$ or tw antibodies$) and (tw immunocompetent$ or tw immunoglobulin$ or tw genotype))) and not mh humanos) or ((mh transmissao de doenca infecciosa or mh parasitologia or pt in vitro or mh marcadores biologicos or ex G07.690.320$ or ex e05.393.760$ or mh ligacao proteica or mh Proteina C-Reativa or mh proliferacao de celulas or mh crescimento celular or mh divisao celular or mh linhagem da celula or ex g04$ or mh estudos soroepidemiologicos or mh Dados de Sequencia Molecular or mh proteinas recombinantes or mh camundongos or mh ratos or mh modelos animais de doencas or mh receptores de quimiocinas or mh macrofagos or mh insetos vetores or mh /tm or mh /et or mh /py or mh /ip or mh /gd or mh /ps or mh /ch or mh /ge or mh /vi or mh /en or mh /pa or mh /ph or mh /im) and mh animal) or (((tw plasmodium and tw falciparum) or tw anopheles or (tw mycobacterium and tw tuberculosis) or (tw mycobacterium and tw leprae) or (tw mycobacterium and tw ulcerans) or (tw trypanosoma and tw cruzi) or (tw trypanosoma and (tw brucei or tw gambiense or tw rhodesiense)) or tw Leishmania or tw Helminths or (tw Wuchereria and tw bancrofti) or (tw Brugia and tw Malayi) or tw Onchocerca or (tw schistosoma and (tw haematobium or tw mansoni or tw japonicum)) or tw Trematoda or tw Fasciola or tw Opisthorchis or tw Clonorchis or tw Paragonimus or tw Fasciolidae or tw Ancylostomatoidea or tw Trichuris or tw Ancylostoma or tw Uncinaria or tw Bunostomum or tw Ascaris or (tw Ascaris and tw lumbricoides) or tw aedes or (tw mycobacterium and tw tuberculosis) or tw hiv or (tw Meningit$ and tw bacteria$) or tw brucella or tw Enterobacteriaceae or (tw bacilos and tw coliformes) or tw ewingella or tw leclercia or tw paracolobactrum or tw sodalis or (tw mycobacterium and tw bovis) or (tw bacillus and tw anthracis) or tw cryptosporidium or tw toxoplasma or (tw virus and tw raiva)) and not mh humanos) or ((mh plasmodium falciparum or mh anopheles or mh Mycobacterium tuberculosis or mh mycobacterium leprae or mh mycobacterium ulcerans or mh trypanosoma cruzi or mh moscas tse-tse or mh Leishmania or mh Wuchereria bancrofti or mh Brugia Malayi or mh Onchocerca or mh schistosoma haematobium or mh schistosoma mansoni or mh schistosoma japonicum or mh Taenia solium or mh Cysticercus or mh Virus da Dengue or mh Mycobacterium tuberculosis or mh bacillus anthracis or mh cryptosporidium or mh toxoplasma or mh virus da raiva) and mh animal))

Implementation Research

(((((tw Implementation or tw operation$ or tw evaluation$ or tw monitoring or (tw community and tw based) or tw participatory) and tw research) or (tw post and tw registration) or ((tw efficiency or tw effectiveness) and tw intervention) or (tw technology and tw transfer) or (tw health and tw system$ and (tw research or tw strenghtening)) or (tw public and tw health and tw intervention) or ((tw prevention or tw control) and tw strateg$) or (tw health and tw services) or (tw access and tw research) or (tw field and tw trial) or ((tw acceptability or tw imputability or tw compliance$ or (tw community and tw based)) and tw health and tw intervention) or (tw community and tw directed and tw intervention) or (tw translation$ and (tw research or tw knowledge)) or (tw knowledge and tw management) or (tw Good and tw practice$) or mh Conhecimentos, Atitudes e Pratica em Saude or mh promocao da saude or mh Avaliacao de Programas e Projetos de Saude or mh Educacao em Saude or mh Controle de Doencas Transmissiveis or pt Ensaio Clinico Fase IV or mh /pc) or (ex n05.715.360.775.175.250$ or mh estudos de coortes or ti cohort$ or mh seguimentos or (tw follow$ and tw stud$) or (tw treatment and (tw failure or tw outcome)) or ((((tw antifungal or tw anti-infective or tw anti-bacterial or tw anti-retroviral or tw antitubercular) and tw agents) or tw antibiotic$ or (tw drug and tw interactions)) and (ti treatment or ti therapy or ti prevention or mh ./tu or mh ./th or mh ./su or mh ./dt)) or (mh recursos em saude or (tw health and tw resources) or mh participacao comunitaria or (tw consumer and tw particip$) or (tw national and tw health and tw program$) or mh programas nacionais de saude or ((ti services or mh /og or ti organization or ti administration)) and (mh /di or tw diagnosis or mh /th or tw therapy or tw treatment or (tw prevention and tw control) or mh /pc or mh /dt)) or (tw useful and tw diagnostic) or (tw prospective and tw studies) or (tw treatment and tw programs) or ((tw diagnosis or tw treatment) and ((tw clinical and tw practice) or tw applicability or tw experience or tw implications)) or (tw clinical and (tw predictors or tw practice or tw analysis or tw profile)) or (tw insecticide-treated or tw nets) or mh mosquiteiros tratados com inseticida or mh controle de mosquitos or (tw mosquito and tw control) or (((tw consumer and tw participation) or tw community) and (tw prevention or tw control)))) and not mh animais)

Product Development

(pt ensaio clinico fase I or pt ensaio clinico fase II or pt ensaio clinico fase III or (tw clinical and tw trial and tw phase and (tw one or tw three or tw two)) or mh avaliacao pre-clinica de medicamentos or mh Relação Dose-Resposta a Droga or (tw double and tw blind and tw trial) or ((tw sequential or tw stratified) and tw trial) or ((tw diagnostic$ or tw drug$ or mh /tu or mh /dt or tw product$ or tw vaccine$ or tw clinical) and (tw test$ or development or mh /ip)) or tw randomized$ or tw crossover or (tw cross and tw over) or tw pharmaco$ or ((tw minimal or tw maximal or tw lethal or tw toxic or tw therapeutic) and tw dose) or mh efeito placebo or (tw placebo and tw effect)) and ct humanos and not ct animais

Malaria/Malária

(ex c03.752.530$ or mh vacinas antimalaricas or mh antimalaricos or mh plasmodium) or (tw malaria or tw plasmodium or tw antimalari$) or (tw anopheles and tw malaria)

Tuberculosis/Tuberculose

(ex C01.252.410.040.552.846$ or MH Vacinas contra a Tuberculose or mh vacina bcg or mh Mycobacterium tuberculosis or tw antitubercul$ or ti tuberculos$ or (tw Mycobacterium and tw tuberculos$)) and not (tw meningitis or tw bovis or tw bovine)

Leprosy/Hanseníase

(ex C01.252.410.040.552.386$ or mh Mycobacterium leprae or (tw Mycobacterium and tw leprae) or (tw hanseniase or tw lepra or tw leprosy) or ((ti doenca or ti disease$ or ti enfermed$ or ti mal) and ti Hansen$))

Buruli Ulcer/Úlcera de Buruli

((mh ulcera de buruli or mh Mycobacterium ulcerans) or (tw ulcer$ and tw Buruli) or (tw Mycobacterium and tw ulcera$))

Chagas Disease

(mh Doenca de Chagas or mh Cardiomiopatia Chagasica or mh Trypanosoma cruzi or (ti chagas and (ti doenca or ti enfermedad or ti disease)) or ((ti Trypanosoma or ti Cardiomiopatia or ti Cardiomyopathy or ti Miocardiopatia or ti Cardiovascular or ti Miocardite or ti Miocarditis or ti Myocarditis) and (ti Chagasica or ti Chagas or ti cruzi)))

Trypanosomiasis/Tripanossomose

(mh Tripanossomiase Africana or mh Trypanosoma brucei gambiense or mh Trypanosoma brucei rhodesiense or mh Moscas Tse-Tse or ((ti brucei or ti gambiense or ti rhodesiense) and (ti Trypanosoma)) or (tw doenca and tw africana and tw sono) or (ti African and ti Sleeping and ti Sickness) or ((ti trypanosomiasis$ or ti tripanossomiase or ti tripanosomiasis$ or ti tripanossomatose) and (ti african$)))

Leishmaniasis/Leishmaniose

(ex C03.752.300.500$ or ex B01.268.475.868.488$ or ti Leishmania or ti leishmaniasis or ti leishmaniose)

Cholera/Cólera

(mh Colera or mh Vibrio cholerae or ti cholera or ti colera or (tw vibrio and tw cholerae))

Dengue

(mh Dengue or mh Virus da Dengue or mh Febre Hemorragica da Dengue or mh Vacinas contra Dengue or mh Aedes or ti dengue or ((ti febre or ti fiebre or ti fever or ti vaccine$ or ti vacina$ or ti vacuna$ or ti aedes) and (ti dengue)))

Dracunculiasis/Dracunculiasis

(mh Dracunculiase or mh Dracunculus Nematode or (tw dracunculias$ or tw dracunculos$ or (tw guinea and tw worm) or (tw verme and tw guine) or (tw verme and tw gusano) or (tw Dracunculus and (tw Nematode or tw nematodo or tw nematoide$ or tw medinensis))))

Communicable Diseases, Emerging/Doenças Transmissíveis Emergentes

(mh Doencas Transmissiveis Emergentes or (ti doencas or ti enfermedades or ti diseases or ti communicab$ or ti infecciosa$ or ti infectou$ or ti transmiss$ or ti transmisib$) and (ti reemergent$ or ti emergent$ or ti emerging))

Schistosomiasis/Esquistossomose

(ex C03.335.865.859$ or mh schistosoma haematobium or mh schistosoma mansoni or mh schistosoma japonicum or (ti Esquistossomose or ti Esquistosomiasis or ti Schistosomiasis or ((ti Schistosoma) and (ti haematobium or ti mansoni or ti japonicum))))

Fascioliasis/Fasciolíase

(mh Fascioliase or mh Fasciola or mh Fasciola hepatica or (ti Fasciolias$ or ti fasciola$ and not (tw Fascíola and tw Chinesa)))

Helminthiasis/Helmintíase

(mh Helmintiase or mh Helmintos or ti Helminthiasis or ti Helmintias$ or ti Helminths or ti Helmintos or ti Nematomor$)

Onchocerciasis/Oncocercose

(mh Oncocercose or mh Oncocercose Ocular or mh Onchocerca) or (ti Oncocercose or ti Oncocercosis or ti Onchocerciasis or ti Onchocerca)

Trachoma/Tracoma

(mh Tracoma or mh Chlamydia trachomatis or tw trachoma or tw tracoma or (ti Conjuntivit$ or ti Egyptian or ti Egipcia or ti Chlamydia) and (ti trachomatis or ti Tracomatosa or ti Granul$ or ti Ophthalmia or ti Oftalmia))

Yaws/Bouba

(mh Bouba or ((tw frambesia or tw framboesia or tw yaws or tw buba or tw bouba) or ((tw Treponema and tw pallidum) and (ti frambesia or ti framboesia or ti yaws or ti buba or ti bouba))))

Zoonoses

(mh Helmintiase or tw Helminthiasis or tw Helmintias$ or (tw helmint$ and (tw infect$ or tw infec$)) or ex c03.335.190.902.185$ or tw Taeniasis or tw teniase$ or tw Cysticercosis or tw cisticercose or tw neurocisticercose or ((tw Taenia or tw cysticercus or tw equinococcus or tw echinococcus or tw cryptosporidium or tw toxoplasma or tw brucella) and (tw infect$ or tw infecc$)) or ex c03.335.190.396$ or tw equinococos$ or tw echinococcosis or ((tw cisto$ or tw cyst$ or tw quiste$) and (tw hidatico or tw hidatidico or tw hydatid or tw hidatidosis)) or tw hidatidose or ex c21.613.415$ or ((tw envenenamento or tw intoxicac$ or tw infect$ or tw infecc$ or tw doenca$ or tw enfermedad$ or tw disease$) and (tw trematod$ or ti Fasciola or ti Opisthorchis or tw Clonorquias$ or ti aliment$ or ti food or tw food-borne or tw foodborne)) or ex c03.335.865$ or tw trematodiases or tw Clonorchiasis or ti Paragonimias$ or tw Fasciolidae or ex c03.335.865.859$ or (tw zoonotic and tw schistosomiasis) or mh schistosoma haematobium or mh schistosoma mansoni or mh schistosoma japonicum or tw Esquistossomose or tw Esquistosomiasis or tw Schistosomiasis or (tw Schistosoma and (tw haematobium or tw mansoni or tw japonicum)) or (ti protozoa$ and (ti infecc$ or ti infect$)) or mh Infeccoes por Protozoarios or tw histomoniase or tw Cryptosporidiosis or tw Criptosporidios$ or ex c03.752.250.800$ or tw toxoplasmos$ or mh virus da raiva or mh vacinas anti-rabicas or tw hidrofobia or mh Raiva or ti raiva or ti rabia or ti rabies or ex c01.252.200.500$ or mh meningite or (tw Meningit$ and tw bacteria$) or mh Brucelose OR tw Brucelos$ or tw Brucellosis or (tw febre and (tw malta or tw ondulante)) or ex c01.252.400.310$ or (tw Enteric$ and bacteria$) or ((tw infect$ or tw infecc$) and (tw enterobacteria$ or tw Enterobacteriaceae or (tw bacilos and tw coliformes) or tw ewingella or tw leclercia or tw paracolobactrum or tw sodalis)) or mh Tuberculose Bovina OR (tw mycobacterium and tw bovis and (tw infect$ or tw infecc$)) or (tw tuberculos$ and tw bovin$) or mh Antraz OR Tw antraz or tw anthrax or mh vacinas contra antraz or (tw bacillus and tw anthracis and (tw infect$ or tw infecc$ or tw toxinfec$)) or tw carbunco or tw baceira or (tw Carbunculo$ and (tw Cutaneo or tw Hematico or tw Inalacional or tw Inalacao or tw maligno or tw Meningeo or tw septicemia)) or (tw Cardadores and tw lana))

Bacterial Infections

(tw Meningit$ and tw bacteria$) or tw brucella or (tw enterobacteria$ or tw Enterobacteriaceae or (tw bacilos and tw coliformes) or tw ewingella or tw leclercia or tw paracolobactrum or tw sodalis) or (tw mycobacterium and tw bovis) or mh bacillus anthracis or (tw bacillus and tw anthracis)

Estratégia opcional para classificação de docts não classificados na estratégia

Basic research

(ti genetic$ or mh /ge or ti cell or ti cells or ti resistant or mh Resistencia a Medicamentos or ((ti resistance or ti resistant) and (ti drug or ti insecticide or ti drugs or ti antibiotic$))) or ((tw virus and tw serotype$) or mh epidemiologia molecular or (tw epidemiology and tw molecular) or mh dna$ or tw mutation or tw cells or tw genotyp$ or tw genes or mh Estudos Soroepidemiologicos or (tw seroepidemiologic and tw studies) or tw seroprevalence or tw sero-epidemiologic or tw morphogenesis or ((tw flagellum or tw flagellar) and (tw distribution or tw motility)) or ti aetiology or (tw environmental and tw risk and tw factors and ti epidemiol$) or ti microbiology or mh /mi or ti mycobacteria or mh /pp)

Implementation research

(ti clinical or ti therapy or ti treatment or ti diagnost$ or mh /th or mh /dt or mh /pc or (ti prevention and ti control)) and (tw strategies or tw strategy or tw surveillance or tw appropriate or tw practice or tw practical or tw feasible or tw feasibility or tw useful or tw availability or mh saude publica or mh politica de saude or ex N03.349$ or (ti health and (tw reform or tw policy or tw planning or tw program$)) or mh Analise Custo-Benefício or (tw Cost-Benefit and tw Analysis) or mh /ec or mh /og) or ((tw vigilancia and tw epidemiologica) or mh saude publica or ((tw recommendation$ or tw program or tw programs or tw effective or tw surveillance) and (tw prevent or tw control$ or tw treatment or tw prophylaxis)) or (tw spatial and tw distribution and tw epidemiol$) or ((ti epidemiology or ti epidemiologic or ti distribution or ti incidence or ti prevalence) and not (tw pharmacoepidemiol$ or (tw virus and tw serotype$) or mh epidemiologia molecular or (tw epidemiology and tw molecular) or mh dna$ or tw mutation or tw cells or tw genotyp$ or tw genes or mh Estudos Soroepidemiologicos or (tw seroepidemiologic and tw studies) or tw seroprevalence or tw sero-epidemiologic or tw morphogenesis or ((tw flagellum or tw flagellar) and (tw distribution or tw motility)) or ti aetiology or (tw environmental and tw risk and tw factors and ti epidemiol$) or ti microbiology or mh /mi or ti mycobacteria or mh /pp)))

Product development

(tw immunodiagnosis or ((tw diagnostic or tw diagnosis) and (tw performance or tw evaluate or tw test or tw tests)) or mh Valor Preditivo dos Testes or mh Sensibilidade e Especificidade or (ti vaccine and (tw development or tw test or tw tests or tw trial))) or tw pharmacoepidemiol$